Washington Heights is on the high ridge in Upper Manhattan that rises steeply north of the narrow valley that carries 133rd Street to the former ferry landing on the Hudson River that served the village of Manhattanville.

The Theater District first began to attract theaters and restaurants to the neighborhood after the Metropolitan Opera House moved to West 39th Street and Broadway in 1883.

It features some of the oldest architecture in downtown Manhattan, and includes the largest concentration of restored early 19th-century commercial buildings in the city.

It is one of only three universities in the New York State metropolitan areas to have schools of law, medicine and engineering, all of which are ranked in the "top 50" according to the US News & World Report.

Morningside Heights is part of the Upper West Side. However, it has been described as part of "Greater Harlem". As the city grows and residents move in and out, neighborhood names change as well.

Midtown Manhattan is the busiest single commercial district in the United States and ranks among the most intensely used pieces of real estate in the world.

Hudson Square is unique among neighborhoods in that a great deal of the land and buildings here are owned by one company, Trinity Real Estate, a wholly-owned subsidiary of Trinity Church.

The park is at the core of both the neighborhood referred to as either Gramercy or Gramercy Park and the Gramercy Park Historic District. The tallest buildings in the area top out at around 20 stories, and older buildings of 3-6 floors are numerous.

The Garment District has been known since the early 20th century as the center for fashion manufacturing and fashion design in the United States, and even the world.

The area slowly grew to encompass all of Italian Harlem, as Italians moved out and Latinos moved in during another wave of Latino immigration after the Second World War. Since the 1950s, East Harlem has been dominated by residents El Barrio.